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Tired of Zolpidem? Meet the sleep medication of the future!

If you've ever taken sleep medications, you probably belong to one of 2 camps: either the sleeping pills well and they provided much-needed relief or you perceived it as a pure waste of money and caused a lot of side effects that left you wondering if there were better options on the market. While there are plenty of sleeping aids available to keep you from your insomnia The pharmaceutical industry has not stopped looking for newer and more effective drugs.

No new prescription hypnotics have come onto the market since 2008, but research is underway in several areas. The brain is a complex entity with about 17 different neurotransmitters involved in the sleep-wake cycle, and once these are all fully understood, drugs will emerge that provide a better solution to sleep disorders.

Below we list some possible treatments that could soon help you fall asleep more easily and wake up rested. In addition, we will add some suggestions of what you can do in the meantime.

For jet lag or shift work

Two clinical trials have shown that a new drug called tasimelteon is in the pipeline. It helped subjects fall asleep faster as well as sleep longer, leading to a better sleep pattern. The drug is a melatonin analogue. Melatonin is the naturally occurring hormone that helps regulate the body's sleep-wake patterns. Unlike the existing one benzodiazepine hypnotic hypnotics like zolpidem and zopiclone, melatonin analogues do not tend to lead to dependence. The tasimelteon manufacturer hopes the product will be available to patients within a few years.

While no drug has been specifically approved to date for helping jet lagged patients, taking melatonin one or two hours before going to bed can aid your body in the transition. It is usually more difficult to set a sleep schedule on flights to the east than on flights to the west. Upon arrival at your destination, you should take melatonin at your preferred bedtime so that your body can adjust.

For age-related sleep problems

As a result of aging, melatonin levels in the brain decrease. Circadin is a new drug developed in Israel. It can help people 55 and older get the sleep they desperately need. By slowly releasing small amounts of melatonin into the brain during the night, this medicine will help people sleep through the night without feeling sleepy the next day. Already available in several European countries, Circadin is expected to be available across Europe in 2009.

In addition to this medication, a thorough examination is always recommended to determine the cause of the insomnia. Often becomes patients cognitive behavioral therapy in combination with light benzodiazepines such as Ambien, Lunesta, or Sonata are recommended. They have relatively few side effects and hardly hinder the patient's alertness during the day.

For those who wake up in the middle of the night

The Ministry is still pending approval for a new drug to help insomnia patients fall back to sleep when they wake up in the middle of the night. The tablet, which dissolves on the tongue in about two minutes, contains 28% of the active ingredient zolpidem. Which we also find in Ambien and the generic version. This lower dose ensures that the effect wears off within three or four hours of taking it, making it easier to wake up in the morning.

Unfortunately this is kind buy zolpidem not yet possible. If you are taking these medications as directed and still wake up in the middle of the night, talk to your doctor about changing your plan. You might consider changing your medications, increasing your dosage, adding a shorter-acting drug to your regimen, or taking half a pill when you wake up at night.

For insomnia

Currently, the drug doxepin is used to treat depression and depression anxiety, but at smaller dosages like 3 to 6 milligrams it has been shown to help with insomnia as well. The drug's sedative power improved the total sleep time of those involved in a clinical trial. Silenor, the proposed brand name, is expected to hit the market next year.

However, if you are now suffering from insomnia, it is advisable to see a therapist or psychologist. There are many clinical studies showing that long-term cognitive behavioral therapy helps people with chronic insomnia. The downside is that it takes at least four to eight sessions for it to start working. A combination of behavioral therapy and short-term medication can thus offer a solution.

For sleep apnea

The severity of sleep apnea may be related to the levels of omega-3 fatty acids in the body, researchers at the University of Missouri in Kansas City reported in a 2008 study.

So there is hope that drug therapies targeting the brain's neurotransmitters could show promise for patients with sleep apnea. The same chemicals that control the sleep-wake cycle can also control the tone and stiffening of the muscles in the throat that keep the airway open. If researchers can develop a pill to activate those neurotransmitters to tighten the throat muscles during the night, the airway will remain open and sleep apnea can be reduced or even avoided.

While it's too early to draw specific guidelines from the University of Missouri research, you can increase your omega-3 intake by adding fish and nuts to your diet.


It is estimated that it takes an average of 12 years and nearly $ 500 million to get a new drug from the lab to the pharmacy. Even if a drug has already been approved, studies on the marketing of the new drug are only just beginning. The fact that these drugs have shown promising results is encouraging, but there is no guarantee that they will solve your specific sleep problems or even make it onto the market. Until you can try them out for yourself, talk to your doctor about healthy habits, relaxation techniques, and current treatment options that can help you get the sleep you need.

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